2016-02-26 · According to the landmark contribution of Farb et al. in 1996, which reported that plaque erosion occurred in 44% of patients who died due to acute MI (with an increased prevalence in women), there has been no firm agreement on the precise prevalence of plaque erosion versus rupture (Figures 1 and 2). 6,7,9 Indeed, this is a key issue because the management of rupture would conceivably entail
Mar 23, 2021 Coronary angiography and OCT revealed plaque erosion with subsequent subtotal thrombotic occlusion of the left anterior descending artery that
1 and. Oct 24, 2019 Aortic Stenosis in FH; Plaque Erosion; CAD Wave Intensity Analysis. — Interventional cardiology news to note. by Nicole Lou, Staff Writer, Apr 23, 2019 Plaque erosion seems to be on the rise as cause of coronary thrombosis, probably due to the changing of the cardiovascular risk profile and Plaque erosion: Towards precision medicine in acute coronary syndromes.
Differential accumulation of proteoglycans and hyaluronan in culprit lesions: insights into plaque erosion. Arterioscler Thromb Vasc Biol . 2002 ; 22 :1642–1648. Plaque erosions are more often observed in younger individuals and smokers compared with plaque ruptures. There have been few angioscopic investigations of plaque erosion.
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The advent of intravascular imaging techniques, particularly optical coherence tomography, has aided understanding • Plaque erosion was the underlying pathology in ¼ of patients with ACS. • Anti-thrombotic therapy without stent implantation effectively reduced thrombus volume and increased flow area without recurrent ischemic events at 1 month. 10 • Randomized trials will be needed to reproduce this pilot data Plaque Erosion as a Mechanism of Acute Coronary Syndromes (ACS) JN Learning™ is the home for CME and MOC from the JAMA Network. Search by specialty or US state and earn AMA PRA Category 1 CME Credit ™ from articles, audio, Clinical Challenges and more.
que erosion.” Pathologically, eroded plaques are rich that lesions responsible for AMI with plaque erosion Plaque rupture and plaque erosion as underlying.
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1,2 Several groups have reported in vivo diagnoses of these underlying pathologies in patients with acute coronary syndrome (ACS) using optical coherence tomography (OCT), a high-resolution intracoronary imaging modality.
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In contrast with plaque rupture, the pathophysiological mechanisms leading to plaque erosion remain poorly understood. The advent of intra … EC sloughing and neutrophil invasion occur secondarily to stasis-induced venous thrombosis, 4 and thrombi precipitated by plaque rupture can produce the appearance of plaque erosion in neighboring segments. 2 The idea that erosions are preceded by plaques deprived of large regions of its endothelial lining may thus be far too simple. Plaque erosion is placed most in the proximal segment and near a bifurcation of the left anterior descending artery. Near a bifurcation is anatomically the most significant predictor of plaque erosion.
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In contrast, plaque erosion most frequently occurs on stenotic plaques in areas of elevated flow. This changes the behaviour of endothelial cells and primes the Nrf2 system, which under normal situations helps protect the endothelium. Smoking is a known risk factor for plaque erosion.
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Oct 15, 2016 The step by step process of plaque rupture.
Plaque erosion is defined as an acute thrombus in direct contact with the intima in an area of denuded endothelium. Thus, plaque events ensue as a result of an intimal fibroatheroma in the coronary artery wall becoming vulnerable to erosion or rupture.